Clin2
NCT07642505Likely a fitRecruiting

L-Citrulline and Tadalafil for Mild Erectile Dysfunction

Erectile Dysfunction

Treatments studied

Part of Kidney & urinary, Mental health clinical trials.

This study tests whether two compounds—L-citrulline (a natural amino acid) and tadalafil (a common erectile dysfunction medication)—work well together for men with mild to moderate erectile problems. The goal is to see if this combination safely improves sexual function.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
133 people
Ages
30 years to 70 years
Study type
Interventional

Who can take part

  • You are a man between 30 and 70 years old
  • You have had erectile dysfunction (difficulty getting or keeping erections) for at least 3 months
  • Your erectile dysfunction is mild to moderate, not severe
  • You are in a stable relationship and willing to attempt sexual activity during the study
  • You can complete questionnaires and attend follow-up visits
  • You do not take nitrates (heart medications) or have serious heart, liver, or kidney problems

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07753720Recruiting· Phase 4
Daily tadalafil with or without another treatment for erectile dysfunction

This study tests whether taking tadalafil daily, either alone or with a second treatment, works better for men with erectile dysfunction who have not responded to on-demand pills. It aims to help men who have not had success with current treatments.

Cairo
NCT05955001Recruiting· Phase 2/Phase 3
Tadalafil for early urinary symptoms after prostate surgery

This trial studies whether daily tadalafil (5 mg) can improve early urinary trouble and erection function after endoscopic prostate tissue removal. It may help men whose urinary symptoms continued even after prior medicine.

Al Mansurah, Dakahlia Governorate
NCT07177326Not yet recruiting· Phase 3
Combining two ED medicines vs. one medicine for erectile dysfunction

This study compares two different treatments for erectile dysfunction (ED): taking two lower-dose medicines (tadalafil and sildenafil) together once daily, versus taking a single higher-dose medicine (tadalafil) once daily. The goal is to see which approach works better and is safer for men with ED.

NCT07537855Not yet recruiting· Phase 2
Botox injections plus tadalafil for erectile dysfunction

This study tests whether injecting Botox (a muscle-relaxing medication) directly into the penis, combined with the oral medication tadalafil (Cialis), can improve erectile dysfunction in men who didn't get enough relief from tadalafil alone. The goal is to see if this combination helps men achieve and maintain erections.

NCT04762082Not yet recruiting· Phase 1
Test gummy tadalafil to see how the body absorbs it

This Phase 1 study tests how different tadalafil gummy-style products move through your body after a single dose. It’s done in healthy adult volunteers and helps scientists understand dosing and absorption safely.

NCT07231185Not yet recruiting· Phase 2
Sildenafil for erectile dysfunction in adult men

This study tests how well sildenafil works for men with erectile dysfunction. You may qualify if you are a man between 18 and 70 with ED for at least 3 months and are sexually active.

Hear when a new Erectile Dysfunction trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.