Clin2
NCT07645157Possibly a fitRecruiting

Sertraline and Probiotics for Teen Depression

Major Depressive Disorder (MDD)Probiotic Intervention

Treatments studied

Part of Mental health clinical trials.

This study tests whether combining an antidepressant medication (sertraline) with special bacteria supplements (probiotics) can help treat depression in teenagers ages 12–18. Researchers believe the probiotics may help the medication work better by improving gut health.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
120 people
Ages
12 years to 18 years
Study type
Interventional

Who can take part

  • You are between 12 and 18 years old
  • You have been diagnosed with major depressive disorder and are currently having a depressive episode
  • You have not tried sertraline before, or if you have, it didn't work well for you
  • You are not taking any other antidepressants right now (must stop at least 5 days before starting)
  • You have not taken probiotics or probiotic foods in the past 2 weeks
  • You have not taken antibiotics or antifungal medicines in the past month

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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