Fish oil supplement with escitalopram for major depression
Part of Mental health clinical trials.
This trial tests whether adding a special fish oil supplement (CreNeuroS) to the antidepressant escitalopram helps improve depression symptoms more than escitalopram alone. If you have moderate to severe depression and are starting or recently started escitalopram, this study may help you find a more effective treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with major depression and are experiencing moderate to severe symptoms.
- You are about to start the antidepressant escitalopram, or have been taking it for no more than 2 weeks.
- You are not at high risk for suicide and have no other major psychiatric conditions like bipolar or schizophrenia.
- You are not currently using fish oil, omega-3, folic acid, or similar supplements, and you do not eat fish 3 or more times per week.
- You do not have severe or unstable medical conditions (like uncontrolled liver or kidney disease), and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether adding acupuncture to a common antidepressant (escitalopram) helps improve depression symptoms more than the medication alone. It aims to see if this combination can be a safe and effective treatment for adults with major depression.
This trial tests whether escitalopram, a common antidepressant, helps people who are experiencing their first episode of depression and have never taken medication for it. It also looks at how the drug works in the brain.
This trial tests whether transplanting healthy gut bacteria (fecal microbiota) can help people with depression that does not respond well to the antidepressant escitalopram. You will first take escitalopram for 2 weeks, and if it doesn't help enough, you may receive either the real transplant or a placebo capsule.
This trial tests if probiotics can help reduce symptoms of mild to moderate anxiety or depression. It is for people aged 18–60 who are not currently taking most anxiety or depression medications and who have not used them in the last 2 weeks (except for escitalopram).
This Phase 4 study tests an “optimized” medication approach for adults with major depressive disorder (unipolar depression) based on how you respond over time. It may help your care team choose treatments more effectively and reduce trial-and-error.
This trial tests a new medicine called LV232 for people with moderate to severe depression. Researchers want to find the best dose and check if it works safely.
Hear when a new Adjunct in the Treatment of Depressive Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.