Personalized myeloma treatment based on response and fitness
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests whether tailoring myeloma treatment based on how well you respond to initial therapy and your overall health status can improve outcomes. You'll receive standard first-line treatment (three drugs: daratumumab, lenalidomide, and dexamethasone) and then be assigned to a personalized pathway based on your response and fitness level.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Newly diagnosed with symptomatic myeloma (a blood cancer affecting plasma cells)
- Not suitable for stem cell transplant as determined by your doctor
- Planned to receive daratumumab, lenalidomide, and dexamethasone as first-line treatment
- Age 18 or older
- Able to provide informed consent and follow a pregnancy prevention plan
- No previous myeloma treatment (except as specified in the study protocol)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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