Skull bone study in infants with craniosynostosis
Part of Bones, joints & muscles, Genetic & congenital clinical trials.
This study looks at the skull bones and stitches (sutures) removed during surgery for craniosynostosis to learn more about their structure. It may help doctors understand better how to treat this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must have a confirmed diagnosis of craniosynostosis (early closure of the skull bones) made by a pediatric neurosurgeon.
- Your child must be receiving care in the neurosurgery department of Prof. Federico Di Rocco at the Hôpital Femme Mère Enfant.
- Your child must be between 3 and 12 months old.
- Your child must not have had any previous surgery on the skull (including bone reshaping or implants).
- Your child must not have had a significant head injury in the last 6 months.
- Your child must not have any metabolic bone disease (like osteogenesis imperfecta or rickets) or other serious medical conditions affecting bone health, and must not have taken certain medications (like steroids or chemotherapy) in the last 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether burosumab and vitamin D affect bone cells before and around the time of craniosynostosis surgery in children. It may help researchers understand treatment options for rare calcium and phosphate bone disorders that can affect skull growth.
This study is building a database of medical information and images from children with certain conditions affecting the face and skull, such as craniosynostosis, achondroplasia, and osteogenesis imperfecta. The goal is to better understand these conditions and improve future care.
This study tests a new 3D-printed guide to help surgeons perform skull reshaping surgery for young children with craniosynostosis (early skull bone fusion). It aims to improve safety and precision during surgery.
This study looks at how general anesthesia may affect “brain injury marker” levels during and after surgery for single-suture craniosynostosis in infants. It may help doctors better understand anesthesia timing and safety for babies having corrective surgery.
This study tests a new treatment called ASO (antisense oligonucleotide) therapy on tissue samples from babies with syndromic craniosynostosis—a condition where skull bones fuse too early due to specific genetic changes. Researchers hope this approach could eventually help prevent or reduce the severity of this condition.
This study looks at eye features in people with craniosynostosis (a condition where skull bones fuse too early). It may help doctors better understand eye problems that can occur with this condition.
Hear when a new Craniostenosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.