Testing pirfenidone for a rare throat condition
Treatments studied
Part of Lungs & breathing clinical trials.
This trial tests if the drug pirfenidone is safe and tolerable for people with idiopathic subglottic stenosis (a narrowing of the windpipe below the vocal cords). It may help reduce the need for repeat throat dilation procedures.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with idiopathic subglottic stenosis (iSGS).
- You have had at least 2 dilation procedures in the past year, or you receive steroid injections every 3 months for your condition.
- You are not currently smoking and are willing to avoid smoking during the treatment.
- You have adequate liver and kidney function (checked by a blood test).
- If you could become pregnant, you agree to use effective birth control and have a negative pregnancy test before starting.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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