Stem cell therapy for gastrointestinal fistulas
Part of Digestive system clinical trials.
This trial tests a new treatment using your own fat cells to help close abnormal connections (fistulas) in the digestive tract. The treatment is done through an endoscope and may help heal these openings without surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a confirmed abnormal connection (fistula) in your digestive tract that is not related to cancer.
- The fistula can be reached and treated with an endoscope (a flexible tube with a camera).
- You are willing to try the stem cell therapy, which may be combined with other endoscopic techniques.
- You can give written consent and are willing to attend follow-up visits.
- You do not have certain types of fistulas (like those related to Crohn's or ulcerative colitis), and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new, less invasive procedure called regenerative endoscopy to repair complex fistulas in people with Crohn's disease. It's for those who haven't gotten better with standard treatments like biologics or surgery.
This trial tests whether injecting donated stem cells into complex anal fistulas can help heal them in people with Crohn's disease. You may qualify if you have a fistula that hasn't improved with standard treatments.
This trial tests whether injecting your own fat-derived cells combined with a skin graft can heal anal fistulas (abnormal passages near the anus) that didn't respond to or came back after a previous cell therapy study. You must have already participated in the ADICROHN-2 study.
This trial tests if a special stem cell treatment (called DB-3Q bmMSC-EVs) can help heal fistulas caused by Crohn's disease. It's for people who have already tried other treatments and still have actively draining fistulas.
This trial tests a new technique where a small amount of your own fat is taken, processed, and injected through an endoscope to help heal long-lasting fistulas (abnormal connections between organs) that haven't healed with other treatments. It's for people with fistulas that affect quality of life.
This trial compares two types of stem cell treatments to help heal complex anal fistulas (abnormal tunnels near the anus). You may be eligible if your Crohn’s-related disease is mostly controlled and the fistula has not fully healed with standard treatments.
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