Periostin protein levels and quality of life in back pain patients
Part of Bones, joints & muscles, Pain clinical trials.
This study looks at how a protein called periostin relates to back function and quality of life in people with disc herniations or spinal stenosis. You'll fill out two questionnaires and have your periostin measured from a blood draw or MRI.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a herniated disc or narrowing of the spine in your lower back
- You have had an MRI of your lower back
- You are able to fill out questionnaires about your pain and daily life on your own
- You do not have certain other health problems like asthma, recent fractures, severe bone thinning, or infections
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests how a common anti-inflammatory drug (NSAID) affects a protein called periostin, which may be linked to spine problems. It could help people with herniated discs or spinal stenosis.
This study looks at a protein called periostin in the discs of the lower back to see if it relates to how worn down the discs are, which might help improve future treatments.
This study looks at whether a protein in your blood, called BDNF, can help predict how well you might do with chronic low back pain. By participating, you may help doctors better understand and treat this condition.
This trial tests whether your own disc cells (nucleus pulposus cells) can help heal a herniated disc and reduce pain. It is for people who have had low back pain for more than six weeks and are scheduled for disc surgery.
This trial is testing a treatment approach for people with long-lasting, painful worn-out discs in the lower back (and sometimes leg pain). It looks for people who tried common non-surgical options without enough relief and who may be headed toward a lumbar procedure.
This trial tests a new drug called rhGDF-6 injected into the discs of your spine to help repair them. If you have had low back pain for at least 3 months despite trying other non-surgical treatments, and your MRI shows disc wear or changes, this study may offer a new option.
Hear when a new Intervertebral Disc Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.