Heart transplant monitoring with extracellular vesicles
Part of Heart & circulation clinical trials.
This study uses tiny particles called extracellular vesicles (which cells release) to check for signs of organ rejection after a heart transplant, aiming for a safer and less invasive alternative to biopsies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are on the heart transplant waiting list or have just had a heart transplant
- You are 18 years or older
- You can understand the study and give written permission to join
- If you are a woman who could become pregnant, you must have a negative pregnancy test before starting
- You have not had any other organ or tissue transplants before
- You are not legally detained or unable to follow study procedures
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study uses advanced heart imaging and blood tests to detect a type of rejection that can happen after a heart transplant. It may help doctors diagnose antibody-mediated rejection earlier and more accurately.
This trial is for people who have had a heart transplant and are having symptoms or need routine invasive check-ups. It tests an approach aimed at better understanding and monitoring “micro-vessel” problems in the transplanted heart.
This trial is studying whether a blood test that measures small molecules called microRNAs can help doctors personalize the medicines used to prevent rejection after a heart transplant. If you qualify, you would help researchers learn how to better match immunosuppression to each patient's needs.
This study looks at whether changes in blood fats (cholesterol and triglycerides) after a heart transplant are linked to the risk of organ rejection. It may help doctors better monitor and protect your new heart.
This study looks at changes in blood and heart biopsy samples to help detect or understand transplant rejection. You may benefit by contributing to research that could improve future rejection screening and care.
This trial tests a special machine that preserves donor hearts for longer periods before transplant. It may help people waiting for a heart transplant who need a heart from a donor that may be older or has some heart risks.
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