Clin2
NCT07673744Possibly a fitRecruiting

Maintenance treatment for myasthenia gravis after efgartigimod

Myasthenia Gravis

Treatments studied

Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.

This trial tests whether a follow-up treatment with ublituximab (given as an infusion) can help myasthenia gravis patients who first received efgartigimod. The goal is to see if it provides lasting control of MG symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
120 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a confirmed diagnosis of myasthenia gravis.
  • You are already eligible to take efgartigimod, based on standard medical guidelines and a blood test.
  • Your MG symptoms significantly affect daily life—either a score of 11 or more on the MG-ADL scale, or a score of 6 to 10 with most trouble coming from things other than eye symptoms.
  • You have not had a previous B-cell depleting treatment (like rituximab) or certain other strong immune therapies.
  • You do not have another active autoimmune disease (like lupus or rheumatoid arthritis) or an immune deficiency.
  • You have not had a bad reaction to efgartigimod or similar drugs in the past.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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