Ear stimulation for depression in Parkinson's disease
Part of Brain & nervous system clinical trials.
This study tests a gentle, non-invasive ear stimulation device (like a small earpiece) that may help improve depression symptoms in people with Parkinson's disease. It uses a nerve in your ear that connects to the brain, and the goal is to see if it can safely boost your mood without medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have been diagnosed with Parkinson's disease by a doctor
- You must have symptoms of depression (feelings of sadness or loss of interest) that are confirmed by a questionnaire
- Your Parkinson's disease medications must have been stable for at least a month before you start
- You must be between 40 and 80 years old
- You must not be currently taking any antidepressant medication
- You must not have significant memory or thinking problems (like dementia)
- You must not have certain serious medical conditions (like severe heart, liver, or kidney disease) or any reason you can't have the ear stimulation device
- You must not have had vagus nerve stimulation treatment in the past month
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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