Study of DR10624 for Very High Blood Fats
Part of Hormones & metabolism clinical trials.
This study tests an experimental drug called DR10624 compared to a placebo in people with severely high triglycerides (fats in the blood). It aims to see if the drug can safely lower these fats and reduce the risk of related health problems like pancreatitis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and your body mass index is between 19 and 45.
- Your fasting triglyceride (fat) levels are very high but below a certain danger level, between 5.65 and 22.60 mmol/L.
- You are not currently taking medicines for weight loss or diabetes that are similar to the study drug (GLP-1, GCGR, or FGF21 agonists).
- You have not had pancreatitis or a rare genetic disorder causing extreme lipid problems.
- You agree to use effective birth control if you are of childbearing age, or to not donate sperm for 3 months after the last dose if male.
- You are willing to keep a stable lifestyle and follow study rules for several months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early-phase trial tests an experimental drug called FXR0906 in healthy adults who have elevated triglycerides (a type of fat in the blood). It aims to see if the drug is safe and how it affects cholesterol and fat levels, which may help prevent heart disease.
This trial tests a new medicine called SRSD216 for people with high levels of lipoprotein (a), a type of fat in the blood that can increase heart disease risk. The study aims to see if the drug is safe and effective at lowering these levels.
This trial tests a new injectable drug called DR10624 for people with very high triglyceride levels. It aims to lower triglycerides and reduce the risk of pancreatitis (inflammation of the pancreas).
This trial tests a new drug, DR10624, to see if it can lower high triglycerides and reduce plaque in the carotid artery (the main artery in your neck). It may help people with both conditions who are also overweight.
This trial tests an investigational medication, MAR001, to see if it can lower high levels of fats in the blood (triglycerides and remnant cholesterol) linked to heart disease. If you have these conditions, this treatment might help reduce your risk.
This trial tests an experimental drug called CS-121 for people with very high triglyceride levels that don't improve with standard treatments. It uses a new gene-editing approach to lower triglycerides and aims to reduce the risk of pancreatitis and other complications.
Hear when a new Severe Hypertriglyceridemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.