Depression, aging, and antidepressants: a belief study
Part of Mental health clinical trials.
This trial studies how depression and antidepressants affect belief updating in older adults. You may join if you are over 65, have major depression, and are starting a new antidepressant. The goal is to learn more about how your brain adjusts beliefs over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older and see a doctor outside the hospital (outpatient).
- You have major depression or bipolar depression (confirmed by a standard interview).
- You are starting a new antidepressant (changing or beginning one).
- You have no memory or thinking problems (a screening test score of 24 or higher).
- You have moderate to severe depression (score of 20 or higher on a depression scale).
- You are enrolled in a health insurance plan and sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how depression affects thinking, memory, and other cognitive abilities over time. You may be asked to complete assessments and allow follow-up visits so researchers can understand what’s happening in the brain and how depression relates to it.
This trial tests a simple, practical therapy called behavioral activation to help older adults with depression feel better. It's done in your local community, not in a hospital.
This study tests whether a combination of cognitive training (brain exercises) and a medication (guanfacine or sertraline) can improve thinking skills in people with depression. It involves MRI scans and computer tasks to understand how your brain responds.
This study tests whether adding a sleep treatment to regular depression medication can improve both mood and sleep in adults aged 55 and older. It may help if you have ongoing depression, sleep problems, and are already taking antidepressant medication.
This trial tests a personalized approach to treating major depressive disorder using assessments and brain imaging to match you with the best therapy. It aims to improve outcomes by tailoring care to your specific needs.
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
Hear when a new Beliefs trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.