Metabolic therapy to improve insulin sensitivity in type 1 diabetes
Part of Hormones & metabolism, Immune system & allergy clinical trials.
This trial tests a drug that may help your body use insulin better and improve how your cells produce energy. It might lead to better blood sugar control and less insulin needed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 69 years old.
- You have had type 1 diabetes for at least 1 year.
- You currently use insulin (multiple daily injections or an insulin pump).
- Your most recent A1c (average blood sugar over 3 months) is below 9.5%.
- Your body mass index (BMI) is between 18.5 and 40.
- You have not had severe low blood sugar or diabetic ketoacidosis in the past 3 months.
- You have no history of breast or ovarian cancer in you or your family.
- You are not taking certain medications (like metformin, GLP-1 agonists, or SGLT2 inhibitors).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an oral medication that may help your body respond better to insulin. It's for people with type 1 diabetes who use an automated insulin pump and are willing to take a daily pill for 12 weeks.
This trial tests an investigational drug that may help preserve the body's ability to make insulin in people with type 1 diabetes. It aims to slow the progression of the disease and reduce the need for insulin injections.
This study tests if adding a non-insulin medication can lower the amount of insulin needed while improving heart and metabolic health in people with type 1 diabetes. It may also help understand how this approach works in people with a genetic form of diabetes (GCK-MODY).
This study tests an experimental medicine called RGB-5088 for people with type 2 diabetes who are already using insulin. The goal is to see if it can safely improve blood sugar control when added to your current diabetes management.
This study tests a new medication, MTX228, to see if it can help people with type 1 diabetes who still make some insulin. It may slow the loss of your own insulin production and improve blood sugar control.
This early-stage study tests a new experimental drug (NNC0487-0111) designed to help regulate insulin levels in adults with type 2 diabetes. Researchers want to see if it works safely and effectively when combined with your current diabetes medications.
Hear when a new Glucose Metabolism Disorders trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.