Clin2
NCT07701122Possibly a fitNot yet recruiting

Sacituzumab tirumotecan for advanced bile duct cancer

Advanced Biliary Tract Cancer(BTC)

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a new drug called sacituzumab tirumotecan for people with advanced bile duct cancer that has grown after previous treatment. The drug targets a protein called TROP2 on cancer cells and may help shrink tumors or slow the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
33 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have advanced bile duct cancer that has spread or come back, and it got worse after at least one prior treatment.
  • You have at least one tumor that can be measured on a scan.
  • You are generally able to take care of yourself (ECOG score 0 or 1).
  • Your cancer cells have the TROP2 protein (a lab test will check this).
  • You have adequate organ and bone marrow function, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07850791Recruiting· Phase 2
Study of two drugs for advanced bile duct or gallbladder cancer

This trial tests a combination of two drugs, sacituzumab tirumotecan and pembrolizumab, for people with advanced bile duct or gallbladder cancer that has grown after previous treatment. The goal is to see if this combination can shrink tumors or slow the cancer's growth.

Beijing, Beijing Municipality
NCT07729033Not yet recruiting· Phase 2
Study of two-drug combo for advanced bile duct or gallbladder cancer

This study tests a new combination of two drugs for advanced bile duct or gallbladder cancer that has not responded to first-line immunotherapy and chemotherapy. The drugs target the TROP2 protein on cancer cells and boost the immune system to fight the cancer.

Tianjin, Tianjin Municipality
NCT07720258Not yet recruiting· Phase 2
Sacituzumab tirumotecan for advanced small bowel cancer

This trial tests a new drug called sacituzumab tirumotecan (also known as MK-2870) for people with advanced small bowel cancer that has stopped responding to standard platinum-based chemotherapy. The drug is designed to target a protein called TROP2 on cancer cells and deliver a chemo-like payload directly to them, which may help shrink or control the tumor.

Fukuoka
NCT07105852Recruiting· Phase 2
A new drug combo for advanced bile duct cancer

This trial tests a combination of two drugs, sacituzumab tirumotecan and pucotenlimab, for people with advanced bile duct cancer (including gallbladder cancer) that cannot be removed by surgery or has spread. The goal is to see if this treatment is safe and works well, especially for those with a protein called TROP2 on their cancer cells.

Hangzhou, Zhejiang
NCT07324629Recruiting· Phase 2
Sacituzumab Tirumotecan for advanced thymus cancer

This trial tests a new drug, sacituzumab tirumotecan, in people with advanced thymic carcinoma that has spread or cannot be removed with surgery. It is for those whose cancer has gotten worse after at least one round of platinum-based chemotherapy.

Shanghai
NCT07343453Not yet recruiting· Phase 2
Sacituzumab tirumotecan for advanced thymus tumors after prior therapy

This study tests a new drug called sacituzumab tirumotecan for people with advanced thymus tumors that have already been treated once. The drug is given as an infusion and may help control the tumor.

Hear when a new Advanced Biliary Tract Cancer(BTC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.