Treating contact lens discomfort with a nasal spray
Part of Eyes & vision clinical trials.
This trial tests a nasal spray (varenicline) to see if it can relieve discomfort and dryness from contact lens wear. If you wear daily disposable soft contacts and experience end-of-day eye dryness, you may be eligible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must wear daily disposable soft contact lenses at least 5 days a week for 6 hours a day.
- You must have discomfort or dryness in your eyes at the end of the day while wearing contacts (score of at least 40 on a 0–100 scale).
- You must be willing to use only the study nasal spray and no other prescription dry eye treatments for 3 months.
- You cannot have had eye surgery in the past year or have certain eye infections or conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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