Clinical trials
Dry Eye clinical trials
Below are recruiting dry eye clinical trials, each written for real people, not researchers. We’re tracking 106 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07659626Recruiting
Long-term effects of Acoltremon for dry eye disease
This study tests a new medication called Acoltremon to see if it helps dry eye symptoms over a long period. If you've had dry eye for a while and used artificial tears, this trial might be for you.
Louisville, KentuckyAges 18 years+ - NCT05865379Recruiting
Tested eye drops for dry eye relief and safety
This trial studies whether BUFY01 eye drops work better than SVS20 for treating dry eye disease. You may be able to join if you have dry eye symptoms for at least 3 months and meet eye exam score and tear-test requirements.
ParisAges 18 years+ - NCT07273747Recruiting
Kelulut honey for eye allergy and dry eye
This study tests if Kelulut honey eye drops can help people with both allergic conjunctivitis (eye allergies) and dry eye symptoms. If you have been diagnosed with eye allergies and still have bothersome symptoms despite treatment, this trial may offer a natural option to explore.
Kota Bharu, KelantanAges 18–40 - NCT07451184RecruitingPhase 4
Comparing eye drops for dry eye relief
This study compares two different eye drop lubricants to see which one works better for people with dry eye symptoms. You would use only the study drops for the whole time and attend a few visits to check your eyes.
Waterloo, OntarioAges 18 years+ - NCT07453212Enrolling by invitation
Food supplement for dry eye caused by meibomian gland issues
This trial tests a food supplement designed to improve dry eye symptoms by targeting the microbiome. It may help if you have dry eye due to meibomian gland problems and are not using contact lenses or certain other eye treatments.
IstanbulAges 18–65 - NCT07413172RecruitingPhase 2
Testing serum tears for severe dry eye
This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.
Miami, FloridaAges 18 years+ - NCT04658238Recruiting
Dry eye study of the eye microbiome and immune system
This trial looks at how changes in the eye’s normal germs (microbiome) and the immune response may relate to dry eye. It may help researchers better understand what drives symptoms and how to improve care.
BernAges 18 years+ - NCT05605314Recruiting
Study different types of dry eye in Sjögren’s
This study looks at patients with Sjögren’s-related dry eye to understand how different subtypes affect tear function and eye symptoms. It may help doctors better sort out dry eye types, which can guide more tailored care.
BeijingAges 18–80 - NCT05865457Recruiting
Testing two eye treatments for dry eye symptoms
This trial compares two different dry-eye eye drops to see which works better and is safe. You may be able to join if you’ve had dry eye for at least 3 months and meet specific eye-test results.
GrazAges 18 years+ - NCT07632534Recruiting
Serum Eye Drops for Severe Dry Eye Study
This study tests a new eye drop treatment made from your own blood serum for severe dry eye that hasn't improved with standard treatments. Researchers will analyze proteins in your tears to understand why this treatment works and who benefits most.
Saint-EtienneAges 18 years+ - NCT06513000Recruiting
Dry eye changes after cataract surgery
This study measures how dry eyes get after cataract surgery. It may help patients know what to expect after their operation.
SohagAges 45 years+ - NCT06543667RecruitingPhase 1
Stem cell eye drops for dry eye treatment
This trial tests a new eye drop made from stem cells to see if it can help relieve dry eye symptoms. It is for people with moderate to severe dry eye who haven't had recent eye surgery or used other eye drops.
TehranAges 18–70 - NCT06696625Recruiting
Nerve stimulation for dry eye relief
This trial tests if mild electrical pulses on the ear can reduce dry eye symptoms. If you have had dry eye for at least 6 months and meet certain eye test results, this non-drug treatment might help.
Beijing, Beijing MunicipalityAges 18–65 - NCT06780293RecruitingPhase 2
Laser acupuncture for dry eye and Sjogren's dry eye
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
Taipei, TaiwanAges 20–75 - NCT06831253Recruiting
Platelet-Rich Plasma Injection for Severe Dry Eye
This trial tests whether an injection of a special concentrate from your own blood (platelet-rich plasma, or PRP) can help calm severe dry eye disease. It’s meant for people whose dry eye has not improved with other treatments.
Nice, Site Principal InvestigatorAges 18 years+ - NCT06841471Recruiting
Role of Corneal Nerves in Dry Eye Disease
This study looks at how the nerves in the front of the eye (corneal nerves) relate to dry eye disease. It compares people with dry eye to those without to understand differences.
OltenAges 18 years+ - NCT06898853Recruiting
Eye drops for dry eye: A 12-week study
This trial tests whether an anti-inflammatory eye drop (ciclosporin A) can help dry eyes by changing immune cells on the eye's surface. It lasts 12 weeks and may be an option for people with moderate to severe dry eye.
Sydney, New South WalesAges 18 years+ - NCT07175909Recruiting
Tear analysis for dry eye diagnosis and management
This study looks at proteins in your tears to better understand and treat dry eye disease. You may qualify if you have dry eye symptoms and certain test results show your eyes are not functioning normally.
Hong KongAges 18–65 - NCT07179055RecruitingPhase 2
A study of VSJ-110 for dry eye disease
This trial tests a new eye drop called VSJ-110 to see if it is safe and effective for treating dry eye, compared to a placebo (inactive drops). It lasts 8 weeks and may help if you have dry eye symptoms.
Newport Beach, CaliforniaAges 18 years+ - NCT07191847RecruitingPhase 4
Stem cell eye drops for dry eye disease
This trial tests whether stem cell fortified eye drops can improve tear film stability, tear volume, and dry eye symptoms. If you have dry eye disease and haven't had eye surgery or certain other eye conditions, you may be able to join.
GizaAges 18–80 - NCT07266948RecruitingPhase 4
How TRYPTYR eye drops affect dry eye symptoms and daily life
This study tests a new eye drop called TRYPTYR to see if it can improve quality of life and daily tasks for people with dry eye disease who are unhappy with their current treatment, Restasis. Participants will stop using Restasis and switch to TRYPTYR for about 4 weeks.
Pittsburg, KansasAges 18–75 - NCT07295691Recruiting
Autologous serum eye drops for dry eye
This trial tests whether eye drops made from your own blood can help treat moderate to severe dry eye that hasn't improved with artificial tears.
CairoAges Up to 18 years - NCT07676084RecruitingPhase 4
Over-the-counter lubricating eye drops for dry eye
This study tests whether over-the-counter lubricating eye drops can improve dry eye symptoms and eye comfort. It compares the drops to no treatment to see how well they work.
Andover, MassachusettsAges 18 years+ - NCT07554911Recruiting
Improving Treatment for Severe Dry Eye Disease
This study helps doctors find better ways to treat severe dry eye disease. Researchers will perform eye exams and ask questions to understand your condition better and optimize your care.
SingaporeAges 21–99
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Dry Eye trials by city
Studies with a site in or near these metro areas.
Dry Eye trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for dry eye?
- Yes. Clin2 currently lists 106 recruiting dry eye studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dry eye trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dry eye trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.