Clin2
NCT07831473Possibly a fitNot yet recruiting

Safety and effects of an investigational dengue vaccine

Randomised Clinical TrialDouble BlindDengueChallenge TestDose Escalation and Safety

Part of Infections clinical trials.

This early-stage trial tests a new dengue vaccine in healthy adults. Participants will receive the vaccine and later be exposed to a weakened dengue virus to see if the vaccine protects them, while being closely monitored for safety and immune response.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
42 people
Ages
18 years to 55 years
Study type
Interventional

Who can take part

  • You must be between 18 and 55 years old.
  • You need to be in good general health, with no major medical conditions.
  • You cannot have had dengue, Zika, West Nile, or yellow fever before.
  • You must be available for about 50 weeks (almost a year) and willing to follow the study schedule.
  • You need a compatible smartphone (iPhone with iOS 15 or newer, or Android 7.0 or newer) to use a study app for daily diaries.
  • Women who can become pregnant must use effective birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07706686Recruiting· Phase 1
Dengue challenge study in people with prior infection

This study tests how the body responds to a mild, lab-made dengue virus in people who have had dengue before. It looks at how the immune system reacts to a second infection, which may help improve future vaccines and treatments.

Bethesda, Maryland
NCT06891950Recruiting· Phase 3
Dengue vaccine study for healthy older adults

This trial tests a new dengue vaccine in adults aged 40 to 79 to see if it can protect them from dengue fever. If you are generally healthy and willing to follow the study schedule, you may be able to join.

Curitiba, Paraná
NCT07412483Recruiting
Dengue infection study in healthy adults

This trial tests how the dengue virus affects healthy adults who have never been exposed to dengue or similar viruses. You would be given a controlled dose of the virus and closely monitored to help researchers understand the infection and develop better treatments or vaccines.

Singapore
NCT06908018Not yet recruiting· Early Phase 1
Testing a safe dengue infection in immune Thai volunteers

This study tests a controlled dengue infection in volunteers who already have immunity to some dengue types. It aims to see how safe it is and how the immune system responds, which could help develop better vaccines.

NCT06006559Recruiting· Phase 2
Testing a new dengue treatment (EYU688) in adults

This trial tests a new experimental drug, EYU688, for adults with dengue fever. It aims to see if the drug is safe and effective. You may qualify if you have early dengue symptoms, have tested positive for dengue, and are otherwise healthy.

Manaus, Amazonas
NCT06551844Recruiting· Phase 2
Adaptive platform trial for new dengue treatments

This trial tests different experimental drugs to treat dengue early. It aims to find which treatment works best and is safe for patients who start within 48 hours of fever.

Kuala Lumpur

Hear when a new Dengue trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.