Tafolecimab for high cholesterol: testing different dosing schedules
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests a new injectable drug called tafolecimab to see if different dosing intervals work well for people with high cholesterol who are already on a stable statin dose. If your cholesterol (LDL-C) is still not at your goal, adding tafolecimab might help.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older.
- You have high cholesterol and have been taking a moderate statin (like atorvastatin 10 mg daily) or a statin plus ezetimibe for at least 4 weeks without changing the dose.
- Your LDL (bad) cholesterol is above your personal target based on your heart disease risk (for example, if you already had a heart attack or stroke, your LDL must be 1.4 mmol/L or higher).
- Your doctor agrees you need an extra medicine (a PCSK9 inhibitor) to lower your cholesterol further.
- You have never taken a PCSK9 inhibitor (like evolocumab, alirocumab, or tafolecimab) before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medication called SHR-1918 for people with high cholesterol who are already on statins. The goal is to see if it can further lower cholesterol and improve health.
This study tests whether starting the cholesterol-lowering drug tafolecimab (a PCSK9 inhibitor) early after a heart procedure (PCI) can help people with acute coronary syndrome. It may help lower LDL cholesterol and reduce future heart risks.
This trial tests a new cholesterol-lowering drug (Tafolecimab) in people who recently had a stroke or mini-stroke caused by plaque buildup in the arteries. The goal is to see if aggressive treatment can reduce the risk of another event.
This trial tests a new medication (QLC7401) for people with high cholesterol that is not well controlled by their current treatment. It aims to see if the drug can help lower LDL-C (bad cholesterol) levels and reduce the risk of heart problems.
This early-phase trial tests a new medication called STX-1150 for people with high LDL cholesterol. It aims to see if the drug is safe and how well it works to lower cholesterol.
This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.
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