Does lower oxygen during lung surgery reduce lung collapse afterwards?
Part of Lungs & breathing clinical trials.
This trial tests whether using a lower amount of oxygen during lung surgery helps reduce the risk of lung collapse after the operation. It may lead to better breathing and faster recovery after your surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must be scheduled for a lobectomy (removal of a lung lobe) using keyhole surgery (thoracoscopic/VATS).
- Your surgery is expected to last more than one hour with one lung collapsed.
- You must not have had any prior lung surgery.
- You must not have significant collapse (atelectasis) on a CT scan before surgery.
- You must not have certain conditions that make breathing support unsafe (e.g., head injury, heart failure, or a collapsed lung).
- You must not need oxygen therapy at home or have moderate to severe COPD.
- Your body mass index (BMI) must be less than 30.
- You must not have had a heart attack, stroke, or have stents in your heart or brain.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a brief suction method during keyhole lung surgery to help the lung collapse better, making it easier for surgeons to operate. It may benefit adults having planned single-port lung surgery.
This study checks if the length of time one lung is ventilated (breathing for you) during chest surgery affects your risk of lung complications after surgery. It may help doctors plan safer surgeries.
This study tests whether using a high-flow nasal cannula (a device that delivers warm, moist oxygen through your nose) after laparoscopic surgery can help prevent or reduce collapsed lung areas (atelectasis) that sometimes occur after anesthesia and surgery. It may help you recover better and avoid breathing problems.
This trial tests if a customized breathing method during surgery reduces breathing problems after the operation. Patients having minimally invasive lung surgery with one-lung ventilation for more than an hour might benefit from this personalized approach.
This trial studies whether using a brain oxygen monitor to guide lower oxygen levels during one-lung ventilation is safe and effective for people having lung surgery. It may help reduce the risk of lung injury while keeping the brain healthy.
This trial tests a new way to set oxygen levels during spine surgery while lying face down. The goal is to see if it can prevent small air sacs in the lungs from collapsing after surgery, which may help you breathe easier.
Hear when a new Atelectasis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.