Clin2
NCT07721857Possibly a fitNot yet recruiting

Immune cell traps in lupus kidney disease

Lupus Nephritis (LN)

Part of Immune system & allergy, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.

This study looks at how certain immune system traps (called neutrophil extracellular traps) relate to lupus kidney inflammation. It compares people with lupus who have kidney involvement to those who don't, to help understand the disease better.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
18 years to 60 years
Study type
Observational

Who can take part

  • Be 18 years or older (any sex)
  • Have a lupus diagnosis that meets standard criteria
  • Have active lupus kidney disease (nephritis) that requires a kidney biopsy as part of routine care
  • Be planning to start standard treatment (like mycophenolate or cyclophosphamide with steroids)
  • Not have other kidney diseases, major infections, or be pregnant or breastfeeding
  • Not have used certain biologic therapies in the past 3 months
  • Not have a history of cancer

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06654024Not yet recruiting
A drug for lupus-related kidney disease

This trial tests a new treatment for people with lupus nephritis, a type of kidney disease caused by lupus. It may help reduce kidney inflammation and protect kidney function.

Assute, Assute
NCT07364396Not yet recruiting· Phase 1/Phase 2
Immune cell therapy for severe lupus with kidney involvement

This trial tests a new kind of treatment called CRC01, which uses your own immune cells modified to attack and calm the overactive immune system that causes lupus. It's for people with severe lupus that affects the kidneys and hasn't improved with standard therapies, and it aims to reduce disease activity and prevent further damage.

NCT07340463Recruiting· Phase 2
Biologics vs standard therapy for lupus kidney disease

This trial tests two biologic drugs (belimumab or telitacicept) compared to a standard treatment (mycophenolate mofetil) for people with active lupus nephritis. The goal is to see if biologics work better at controlling kidney inflammation over 6 months.

Nanjing, Jiangsu
NCT07130448Not yet recruiting
Blood test markers for kidney problems in lupus

This study looks at two blood tests (albumin/globulin ratio and platelet/albumin ratio) to see if they can help understand lupus nephritis, a serious kidney problem caused by lupus. If you have lupus nephritis, your participation may help improve how doctors monitor and manage this condition.

NCT06975787Recruiting· Phase 1
A New Bispecific Antibody for Lupus Nephritis

This trial is testing a new type of medicine called a 'bispecific antibody' for people whose lupus nephritis has not responded to standard treatments or keeps coming back. The goal is to find a safe dose that might better control the kidney inflammation.

San Francisco, California
NCT07505576Not yet recruiting
Antibody test for lupus kidney disease activity

This study looks at whether a blood test for a specific antibody can help doctors understand how active lupus kidney disease is. It may help guide treatment decisions for people with lupus nephritis.

Hear when a new Lupus Nephritis (LN) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.