Off-pump mitral valve repair through the heart
Part of Digestive system clinical trials.
This trial tests a new way to repair a leaky mitral valve without stopping the heart or using a heart-lung machine. The surgery is done through a small cut in the heart's lower chamber. It may be an option for people with severe degenerative mitral regurgitation who are not good candidates for standard open-heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 years old or older.
- You have severe degenerative mitral regurgitation (a leaky mitral valve caused by a problem with the valve flaps).
- Your mitral valve shape allows the doctor to fix the leak without putting too much tension on the valve.
- You are willing to follow the study procedures and come back for check-ups.
- You do not have other serious heart valve problems, a weak heart pump, or a need for other heart surgery at the same time.
- You have not had prior heart valve surgery (except a past stent or balloon angioplasty) and have not had a stroke or heart attack in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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Other trials that look related to this one.
This study tests a new device, MRace, for people with severe functional mitral regurgitation, a condition where the heart's mitral valve doesn't close fully, causing blood to leak backward. The trial is for patients who have unusual heart structures that make the standard clip procedure difficult. The goal is to see if MRace can safely and effectively fix the leak and improve symptoms.
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