Off-pump mitral valve repair through the heart
Part of Digestive system clinical trials.
This trial tests a new way to repair a leaky mitral valve without stopping the heart or using a heart-lung machine. The surgery is done through a small cut in the heart's lower chamber. It may be an option for people with severe degenerative mitral regurgitation who are not good candidates for standard open-heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 years old or older.
- You have severe degenerative mitral regurgitation (a leaky mitral valve caused by a problem with the valve flaps).
- Your mitral valve shape allows the doctor to fix the leak without putting too much tension on the valve.
- You are willing to follow the study procedures and come back for check-ups.
- You do not have other serious heart valve problems, a weak heart pump, or a need for other heart surgery at the same time.
- You have not had prior heart valve surgery (except a past stent or balloon angioplasty) and have not had a stroke or heart attack in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing a new device to help people with severe mitral regurgitation (a leaky heart valve) who cannot have open-heart surgery or a valve clip. The device is placed using a thin tube through a blood vessel, and aims to improve symptoms and quality of life.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This trial tests a new device to fix a leaky mitral valve in people with moderate to severe leakage who are too high-risk for open-heart surgery. It aims to improve heart function and symptoms.
This trial tests a new device that replaces a damaged mitral heart valve without open-heart surgery. It aims to help people whose leaky valve causes symptoms like shortness of breath or fatigue, and who cannot have standard treatments.
This trial studies a new way to replace a damaged mitral heart valve using a catheter (a thin tube), instead of open-heart surgery. It may help people who have severe leaking of the mitral valve but are considered too high-risk for surgery.
This trial tests a catheter-based procedure to repair a leaking mitral valve in people who are in severe heart shock and need medication support. The goal is to reduce the valve leak and see if it helps patients stabilize and recover.
Hear when a new Mitral Valve (MV) Regurgitation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.