Repairing a leaking mitral valve in severe heart shock
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests a catheter-based procedure to repair a leaking mitral valve in people who are in severe heart shock and need medication support. The goal is to reduce the valve leak and see if it helps patients stabilize and recover.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your legal decision-maker) can sign consent in writing
- You are 18 years or older
- You are in cardiogenic shock that still needs strong heart-support medicines (or you can’t come off breathing/ventilator help due to lung fluid for at least 24 hours)
- Your mitral valve leakage is severe enough (3+ or more) on a special ultrasound from the esophagus (TEE)
- The heart team believes your heart valve shape is suitable for the catheter repair and may reduce leakage to less than 3+
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
This trial studies a minimally invasive device meant to fix a badly leaking mitral valve (mitral regurgitation) without open-heart surgery. It may be an option if you’re considered too high-risk for standard surgery and your heart anatomy fits the device.
This study looks at how long a new mitral valve treatment/device can stay working in people with moderate-to-severe or severe mitral valve leak. It may help avoid or delay surgery for people considered higher risk for mitral valve repair.
This trial tests a less invasive procedure (edge-to-edge mitral valve repair) for people with ATTR-CM and a leaky mitral valve. It aims to see if this repair can help improve symptoms compared to standard medical therapy alone.
This trial studies a catheter-based procedure to replace the mitral valve in people with severe (or specific moderate) mitral valve leakage that causes symptoms. It may help by reducing leaking and related symptoms when standard surgery or less invasive fixes aren’t suitable for you.
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