Clin2
NCT07726199Possibly a fitRecruiting

Neck treatment approaches for oral cancer without neck spread

Oral Squamous Cell Carcinoma (OSCC)

Part of Cancer, Mouth & dental clinical trials.

This study compares different ways to treat the neck in patients with early-stage oral cancer that hasn't spread to the neck. The goal is to find which approach works best while keeping side effects low.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
267 people
Ages
21 years to 75 years
Study type
Interventional

Who can take part

  • You are 21 years or older.
  • You have squamous cell carcinoma of the mouth or tongue that hasn't spread to the neck lymph nodes.
  • Your tumor stage is T1 to T4, but no signs of neck spread on scans or exam.
  • You are generally healthy (able to walk and do light work).
  • You have not had radiation or surgery to the neck before, and this is your first cancer diagnosis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05774483Recruiting
Check nodes in early mouth cancer using a biopsy or planned neck surgery

This trial studies two ways to check whether early oral cavity cancer has spread to nearby neck lymph nodes. It compares sentinel node biopsy versus limited elective neck dissection to see which approach is more useful for people with node-negative tongue or inner-cheek cancers.

Mumbai, Maharashtra
NCT07028918Not yet recruiting· Early Phase 1
Low-dose radiation with immunotherapy and chemo for oral cancer

This trial is testing a combination of low-dose radiation, immunotherapy, and chemotherapy for people with advanced oral cancer that hasn't been treated before. The goal is to see if this approach can help control the cancer and possibly improve outcomes.

NCT07717307Recruiting
Comparing two neck surgeries for oral cancer spread

This trial tests whether a smaller neck surgery works as well as a larger one for people with oral cancer that has spread to one lymph node. The goal is to see if less extensive surgery can reduce side effects while still controlling the cancer.

Kolhāpur, Maharashtra
NCT07127614Not yet recruiting
Managing neck lymph nodes for oral cancer

This study compares how doctors manage the lymph nodes in your neck when treating early-stage oral cancer that has grown a little deeper. The goal is to find the best way to prevent or treat any hidden spread of cancer.

Cairo
NCT05806073Not yet recruiting
Early neck surgery for oral cancer with one affected lymph node

This trial compares two ways to treat the neck when oral cancer has spread to one lymph node. It looks at whether doing surgery right away or waiting until problems appear leads to better outcomes.

NCT06623266Recruiting
Observation vs. neck surgery for early mouth cancer

This study compares two approaches for early-stage mouth cancer: careful observation of the neck versus a preventive surgery to remove neck lymph nodes. The goal is to see which strategy works better to prevent cancer from spreading.

Shanghai

Hear when a new Oral Squamous Cell Carcinoma (OSCC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.