Sepsis and blood vessel injury study
Part of Infections clinical trials.
This trial is testing a new approach to understand how sepsis (a severe infection) damages blood vessels. It looks at tiny particles released by cells and a protein called PLIN3 to see if they can help protect blood vessels in patients with sepsis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed or suspected infection (like pneumonia, a UTI, or a bloodstream infection).
- Your organ failure score (SOFA) has increased by at least 2 points since you were admitted to the hospital.
- You are between 18 and 80 years old.
- You are not pregnant.
- You do not have cancer or other diseases that could affect blood vessel cells.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a special fluid given through a vein can protect and repair the lining of your blood vessels during sepsis. Sepsis is a dangerous reaction to an infection that can damage organs. This study aims to see if this treatment helps patients in the intensive care unit (ICU) recover better.
This study looks at blood vessel cells in three groups: healthy adults, patients having major surgery, and critically ill patients with sepsis. It aims to understand how these cells change in different types of inflammation.
This trial tests a special way to monitor tiny blood vessels (microcirculation) in patients with sepsis. The goal is to see if early treatment based on these readings can help improve recovery.
This study uses special blood testing to learn what is happening in the immune system during sepsis in children and how it may relate to organ injury. Your results may help doctors recognize and treat sepsis earlier and more accurately.
This study tests a new drug (BAY 3389934) for people with sepsis who also have a blood clotting problem. It aims to find the right dose and make sure the drug is safe.
This study looks at how sepsis affects your heart and blood vessels. You may be eligible if you have a serious infection that is not responding to fluids and you need medicine to keep your blood pressure up.
Hear when a new Sepsis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.