Study of blood vessel cells in different inflammatory conditions
Part of Heart & circulation, Infections clinical trials.
This study looks at blood vessel cells in three groups: healthy adults, patients having major surgery, and critically ill patients with sepsis. It aims to understand how these cells change in different types of inflammation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are either a healthy volunteer, scheduled for major surgery, or critically ill with sepsis in the ICU.
- You are able to give consent to participate.
- You do not have certain inflammatory diseases like arthritis, diabetes with organ damage, or heart disease (unless you are in the surgery or critically ill group).
- You are not taking immune-suppressing medications or have recently had chemotherapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing a new approach to understand how sepsis (a severe infection) damages blood vessels. It looks at tiny particles released by cells and a protein called PLIN3 to see if they can help protect blood vessels in patients with sepsis.
This trial tests if a special fluid given through a vein can protect and repair the lining of your blood vessels during sepsis. Sepsis is a dangerous reaction to an infection that can damage organs. This study aims to see if this treatment helps patients in the intensive care unit (ICU) recover better.
This trial tests a special way to monitor tiny blood vessels (microcirculation) in patients with sepsis. The goal is to see if early treatment based on these readings can help improve recovery.
This study looks at how sepsis affects your heart and blood vessels. You may be eligible if you have a serious infection that is not responding to fluids and you need medicine to keep your blood pressure up.
This study looks at how the body’s blood-related immune system “switches on” in unusual ways after a major injury or elective hip repair. The researchers hope this helps them understand who is at risk for complications and why, by measuring changes in your blood around the time of surgery or hospital treatment.
This study collects information from the blood of people in intensive care, to better understand what is happening in the body during sepsis or serious infection. It may help researchers find ways to monitor disease and improve care over time.
Hear when a new Sepsis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.