Nerve block before knee replacement for better recovery
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests if a nerve block given a few weeks before knee replacement surgery can improve pain and function after the operation. It is designed for people who have certain risk factors that might make recovery harder.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old
- You are scheduled for an elective total knee replacement
- You can have the nerve block 2 to 6 weeks before your surgery
- You have at least one of these: a BMI over 35, diabetes treated with insulin, an anxiety disorder, treated depression, widespread pain or central sensitization, chronic pain elsewhere, catastrophizing thoughts, a sleep disorder, severe pain (score 7+), poor knee function (OKS 25 or less), limited daily activity (WOMAC 50+), a previous knee replacement on the other side, or a condition called complex regional pain syndrome in the knee
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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