Nerve Block for Pain Relief During Knee Replacement
Part of Bones, joints & muscles clinical trials.
This study tests whether blocking a specific nerve in the knee can reduce pain and improve recovery after total knee replacement surgery. You would receive this nerve block alongside standard anesthesia to see if it helps you need fewer pain medications afterward.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate-to-severe knee arthritis (grades II–IV) and are scheduled for primary total knee replacement surgery
- You are between 18 and 80 years old
- You are in generally good health (ASA grade I–III, meaning no serious heart, lung, or organ problems that would make surgery very risky)
- You can receive spinal anesthesia (numbing injection in the lower back) during surgery
- You have not taken prescription opioid pain medications regularly (more than 3 months) before surgery
- You do not have a bleeding disorder or allergy to local anesthetics
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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