Nerve Block for Pain Relief During Knee Replacement
Part of Bones, joints & muscles clinical trials.
This study tests whether blocking a specific nerve in the knee can reduce pain and improve recovery after total knee replacement surgery. You would receive this nerve block alongside standard anesthesia to see if it helps you need fewer pain medications afterward.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate-to-severe knee arthritis (grades II–IV) and are scheduled for primary total knee replacement surgery
- You are between 18 and 80 years old
- You are in generally good health (ASA grade I–III, meaning no serious heart, lung, or organ problems that would make surgery very risky)
- You can receive spinal anesthesia (numbing injection in the lower back) during surgery
- You have not taken prescription opioid pain medications regularly (more than 3 months) before surgery
- You do not have a bleeding disorder or allergy to local anesthetics
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two types of numbing injections (nerve blocks) around the knee to help manage pain after total knee replacement surgery. The goal is to see if these injections reduce pain and improve recovery compared to standard pain treatment.
This study compares two ways to manage pain after knee replacement surgery: one uses a nerve block around the knee (adductor canal block), and the other adds an extra shot or nerve block. The goal is to see which approach works better for controlling pain and helping you recover.
This study compares two different nerve-blocking anesthesia techniques to see which one controls pain better after knee replacement surgery. Both methods are designed to numb the area around your knee so you need less pain medication afterward.
This study compares two ways to manage pain after total knee replacement, using nerve blocks (injections that numb the nerves). One method combines a block near the upper thigh with a block behind the knee; the other combines the same upper-thigh block with a different block around the knee. The goal is to see which provides better pain relief and helps you recover more comfortably.
This trial tests two types of nerve blocks (numbing injections around the knee) to see which works best for pain control after knee replacement surgery. Both approaches use the same anesthesia method, and researchers want to learn if adding an extra nerve block helps reduce pain and improve recovery.
This study compares two ways to manage pain after knee replacement surgery: local numbing medicine injected into the knee versus numbing several nerves in the leg. The goal is to find which method provides better pain control and recovery.
Hear when a new Osteoarthritis (OA) of the Knee trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.