Vonoprazan Alone or With Itopride for Stomach Discomfort
Treatments studied
Part of Digestive system clinical trials.
This trial tests if a new stomach acid blocker (vonoprazan) works better alone or with a medicine that helps stomach movement (itopride) for people with ongoing stomach discomfort. It aims to find a better treatment for functional dyspepsia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with functional dyspepsia (stomach pain or discomfort without a clear cause) for at least 3 months, with symptoms most days of the week.
- You had a stomach camera test (endoscopy) in the last 3 months that showed no serious problems, only minor irritation or normal findings.
- You tested negative for H. pylori (a common stomach bacteria) using a breath test or a test during the endoscopy.
- You have not taken any acid-reducing medicines (like omeprazole, pantoprazole) for the past 2 weeks.
- You do not have other stomach or gut conditions (like irritable bowel syndrome, ulcers, or cancer), uncontrolled diabetes, or major depression.
- You are not pregnant, breastfeeding, and do not drink alcohol or smoke.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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