Treatment
Vonoprazan clinical trials
We’re tracking 29 recruiting studies that include Vonoprazan, each written for real people, not researchers, below.
Recruiting studies
- NCT06929962RecruitingPhase 4
VA dual sequential therapy for H. pylori gastritis
This trial tests a new two-step antibiotic treatment for adults with chronic gastritis caused by H. pylori bacteria. If you have not been treated for H. pylori before and are between 18 and 70, you may be able to join.
Nanjing, JiangsuAges 18–70 - NCT07179159Recruiting
14-day stomach infection treatment study
This study compares two treatments for an H. pylori stomach infection: taking two medicines (vonoprazan and amoxicillin) versus taking four medicines. Both treatments are given for 14 days.
Jinan, ShandongAges 18–70 - NCT06349486Recruiting
Comparing new treatments for H. pylori infection
This trial compares three different medication combinations to see which works best for treating H. pylori infection. If you have H. pylori and haven't been treated yet, you may be able to join.
Kaohsiung CityAges 18 years+ - NCT07731542Recruiting
Vonoprazan Alone or With Itopride for Stomach Discomfort
This trial tests if a new stomach acid blocker (vonoprazan) works better alone or with a medicine that helps stomach movement (itopride) for people with ongoing stomach discomfort. It aims to find a better treatment for functional dyspepsia.
Hyderabad, TelanganaAges 20–50 - NCT07306988RecruitingPhase 4
Treating H. pylori to improve metabolic syndrome
This trial tests whether treating H. pylori infection can help improve metabolic syndrome (a group of conditions like high blood sugar, abnormal cholesterol, and high blood pressure). It aims to understand how treatment changes your gut bacteria and overall health.
Nanjing, JiangsuAges 18–65 - NCT07045688Recruiting
Vonoprazan for Helicobacter pylori infection
This trial tests vonoprazan-based treatments to see if they can effectively clear H. pylori infection. It may help if you have not been treated for H. pylori before.
SohagAges 19 years+ - NCT07752407RecruitingPhase 3
Heartburn relief study for people with non-erosive GERD
This study tests a new medicine called vonoprazan to see if it can reduce episodes of heartburn in people who have GERD but no damage to their esophagus. It compares the medicine to a placebo (a pill with no active ingredient) over 24 weeks.
Mentor, OhioAges 18 years+ - NCT06564246RecruitingPhase 4
Comparing Vonoprazan vs. Pantoprazole for GERD
This trial tests a newer medication called vonoprazan against the standard treatment pantoprazole for patients with gastroesophageal reflux disease (GERD). The goal is to see which one works better for controlling symptoms like heartburn and acid reflux over 8 weeks.
GizaAges 17–60 - NCT07576959RecruitingPhase 3
Bismuth with dual therapy for H. pylori infection treatment
This trial tests whether adding bismuth (a mineral compound) to standard two-drug therapy helps cure H. pylori, a common stomach bacteria that can cause ulcers and inflammation. The goal is to see if this combination works better than dual therapy alone.
TaipeiAges 20 years+ - NCT06723197RecruitingPhase 4
Comparing treatment lengths for H. pylori infection
This trial compares different lengths of treatment with two or four medications to see which works best for clearing H. pylori, a stomach bacteria that can cause ulcers. It is for people who have not been treated for this infection before.
Jinan, ShandongAges 18–70 - NCT07537634RecruitingPhase 4
New stomach acid medicine versus standard treatment for H. pylori infection
This trial compares two different antibiotic combinations to treat H. pylori, a common stomach bacteria that causes indigestion and ulcers. One uses a newer acid-blocking medicine (vonoprazan) and the other uses a standard one (esomeprazole), both paired with antibiotics.
DhakaAges 18 years+ - NCT07437768Enrolling by invitation
Vonoprazan test for acid reflux that doesn't respond to standard medicine
This trial tests a medicine called vonoprazan for people whose acid reflux symptoms (like heartburn or coughing) don't get better with usual treatment. It aims to see if vonoprazan can help control those symptoms.
New Taipei City, TaiwanAges 20–75 - NCT07358130Recruiting
Comparing two treatments for H. pylori infection
This trial tests two different ways to treat Helicobacter pylori (H. pylori), a bacteria that can cause stomach ulcers. One treatment combines three medicines (bismuth, amoxicillin, and vonoprazan), and the other uses four medicines (bismuth quadruple therapy). The goal is to see which works better.
Kaohsiung CityAges 18 years+ - NCT07275827RecruitingPhase 3
Testing 3 treatments for H. pylori infection
This study compares two different acid-reducing medications, given with or without zinc, to see which is safer and works best for treating H. pylori. All treatments are combined with two antibiotics.
Shibīn al KawmAges 19 years+ - NCT07275632RecruitingPhase 1/Phase 2
Testing vonoprazan to prevent delayed kidney function after transplant
This trial tests whether a medicine called vonoprazan fumarate can help prevent delayed kidney function after a first kidney transplant from a deceased donor. It is for people who are ready to follow standard post-transplant care.
ChongqingAges 18 years+ - NCT07267260RecruitingPhase 2
Vonoprazan to prevent ulcers after variceal banding
This trial tests whether vonoprazan can reduce ulcers caused by a procedure that ties off enlarged veins in the esophagus (variceal band ligation). It is meant for people with liver cirrhosis who are scheduled to receive this treatment.
Lahore, Punjab ProvinceAges 18–75 - NCT07242456RecruitingPhase 2/Phase 3
Comparing two treatments for H. pylori infection
This study tests two different combinations of medications to treat H. pylori, a stomach bacteria that can cause ulcers. You would take one of the two combinations for a short time to see which works better at getting rid of the infection.
Hangzhou, ZhejiangAges 18–70 - NCT07068607RecruitingPhase 4
Comparing two treatments for H. pylori infection
This study tests whether a new stomach acid medicine called vonoprazan, combined with different antibiotics, works better than standard treatments to clear an H. pylori infection. It is for people who have never been treated for H. pylori and want to try a shorter, simpler treatment course.
Xi'an, ShaanxiAges 18–70 - NCT06959368RecruitingPhase 4
New H. pylori treatment vs standard triple therapy
This trial compares a newer drug (vonoprazan) plus antibiotics to the standard triple therapy for eradicating H. pylori infection in the stomach. It may be a good option if you have stomach symptoms like indigestion, acid reflux, or a non-bleeding ulcer and have not been treated for H. pylori before.
Hyderabad, TelanganaAges 18–80 - NCT06660342Recruiting
Safety of vonoprazan in pregnant women study
This study looks at the safety of vonoprazan (a medicine for acid reflux) when taken during pregnancy. It follows pregnant women who took the drug and those who didn't, to see how it affects mothers and their babies.
Wilmington, North CarolinaAges 15–50 - NCT04713670RecruitingPhase 4
Tested medicines to cure new H. pylori infection
This trial compares different stomach-medicine combinations to eliminate a new (first-time) H. pylori infection. It may help find the most effective treatment approach for people who have never tried eradication therapy before.
TaipeiAges 20 years+ - NCT07439445Recruiting
Simplified treatment for H. pylori guided by a stool test
This trial tests a simpler two-drug treatment for H. pylori infection, chosen based on a stool test that checks if the bacteria are resistant to clarithromycin. It may help people who have not been treated before avoid unnecessary antibiotics.
Beijing, Beijing MunicipalityAges 18–70 - NCT07344506RecruitingPhase 4
Cure H. pylori: New combination therapy for stomach infection
This trial tests a new combination of medications to treat H. pylori, a common stomach infection that can cause ulcers. It aims to find a more effective treatment with fewer side effects.
KarachiAges 18 years+ - NCT07293910RecruitingPhase 2
Comparing stomach acid drugs for clearing H. pylori infection
This trial tests different combinations of stomach acid-reducing drugs, vitamin D or probiotics, to see which works best for clearing an H. pylori infection. H. pylori is a common stomach bacteria that can cause ulcers or stomach discomfort.
Shibīn al KawmAges 18–80
What Vonoprazan is being studied for
Conditions with recruiting Vonoprazan studies.
Common questions
- Are there clinical trials studying Vonoprazan?
- Yes. Clin2 currently lists 29 recruiting studies that include Vonoprazan, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Vonoprazan trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Vonoprazan an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Vonoprazan or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.