Semaglutide and brain response to food in obesity with food addiction
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 19 and 50 years old.
- You need to have a body mass index (BMI) of 30 or higher, or a BMI of 27 to 30 with a weight-related health issue like high blood pressure or diabetes.
- You should have at least a mild food addiction tendency, based on a standard questionnaire.
- You cannot have taken any medications that affect weight or dopamine in the last 2 months.
- You cannot be pregnant, breastfeeding, or planning to become pregnant.
- You must not have certain serious medical conditions, such as severe kidney or liver problems, heart failure, pancreatitis, or thyroid disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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