Semaglutide and brain response to food in obesity with food addiction
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 19 and 50 years old.
- You need to have a body mass index (BMI) of 30 or higher, or a BMI of 27 to 30 with a weight-related health issue like high blood pressure or diabetes.
- You should have at least a mild food addiction tendency, based on a standard questionnaire.
- You cannot have taken any medications that affect weight or dopamine in the last 2 months.
- You cannot be pregnant, breastfeeding, or planning to become pregnant.
- You must not have certain serious medical conditions, such as severe kidney or liver problems, heart failure, pancreatitis, or thyroid disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if a medication called semaglutide can help people with obesity lose weight by changing the bacteria in their gut. You may be able to join if you have obesity, have tried to lose weight before, and are generally healthy.
This study tests a medication called semaglutide (which helps with weight loss) in people with obesity who have struggled to lose weight before. It will see how much weight participants can lose while taking the drug.
This study looks at how genetics may affect your body’s early response to oral semaglutide, a weight-related diabetes medicine. You may be considered if you are overweight (or overweight with prediabetes) and can safely take part in the research.
This study tracks how semaglutide (an injectable medication that reduces appetite) helps adults lose weight in everyday life. Researchers want to understand how well it works and how safe it is for people starting the treatment.
This study tests an injectable medication called semaglutide to help with weight loss in people with a BMI of 28 or higher who have struggled to lose weight before. It compares the study drug to a similar approved weight loss medicine (Wegovy).
This trial studies how brown fat (a type of body fat) changes after starting semaglutide for weight loss. You may help researchers understand how this medication affects the body’s energy use, which could improve weight-loss treatments.
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.