Epinephrine injection during prostate surgery for large prostates
Treatments studied
Part of Kidney & urinary clinical trials.
This study tests whether injecting a drug called epinephrine into the prostate during surgery can improve outcomes for men with large prostates. It aims to reduce bleeding and make the surgery safer and more effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having a type of prostate surgery called TURP (transurethral resection of the prostate).
- Your prostate size is between 80 and 100 grams (about the size of a large peach or bigger).
- You have tried medication for your prostate symptoms but it hasn't helped enough.
- You do not have severe heart problems, uncontrolled high blood pressure, or bleeding disorders.
- You have not taken finasteride or dutasteride (5-alpha reductase inhibitors) in the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether using a guided water injection during prostate surgery helps remove the enlarged prostate more safely and effectively than the standard surgical method. It may help men with significant urinary symptoms who haven't improved with medication.
This trial tests two surgical approaches for enlarged prostate—one specifically designed to preserve the ability to ejaculate and a standard approach—in men with urinary symptoms who haven't improved with medication. You'll be asked about sexual and urinary function before and after surgery.
This trial compares two minimally invasive surgical treatments for benign prostatic hyperplasia (an enlarged prostate that causes urinary problems). Both approaches aim to relieve urinary symptoms while preserving your ability to ejaculate normally.
This trial tests whether a one-time epinephrine medicine injection can help prevent delayed bleeding after an ERCP procedure called sphincterotomy. You may be considered if you had only brief bleeding right after the procedure and you don’t have certain bleeding-risk conditions.
This trial tests a short course of 'epigenetic therapy' (drugs that change how genes work) given before prostate removal surgery. The goal is to see if it can improve treatment effects and help shrink or control the tumor.
This trial compares two surgical techniques for treating an enlarged prostate (BPH) when medication hasn't worked. It looks at which method—bipolar TURP or bipolar enucleation—may be safer and more effective for men with moderate to severe symptoms.
Hear when a new Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.