Treatment
Epinephrine clinical trials
We’re tracking 40 recruiting studies that include Epinephrine, each written for real people, not researchers, below.
Recruiting studies
- NCT04085913Enrolling by invitationEarly Phase 1
Test shot to reduce opioid use after thyroid or parathyroid surgery
This early-phase study tests whether an injection given during thyroid or parathyroid surgery can lower how much opioid pain medicine you need afterward. It may help some people manage pain with less opioid medication.
Columbia, MissouriAges 18 years+ - NCT07733167RecruitingPhase 3
Epinephrine injection during prostate surgery for large prostates
This study tests whether injecting a drug called epinephrine into the prostate during surgery can improve outcomes for men with large prostates. It aims to reduce bleeding and make the surgery safer and more effective.
Banhā, Qalyubia GovernorateAges 40 years+ - NCT07480889RecruitingPhase 3
Low-dose epinephrine for blood pressure stability during c-section
This trial tests if a tiny dose of epinephrine given before a spinal anesthesia infusion can help keep your blood pressure steady during a planned cesarean section. It aims to prevent drops in blood pressure that can occur after spinal anesthesia.
CairoAges 18–35 - NCT07089251RecruitingPhase 4
Epinephrine and tranexamic acid in knee replacement surgery
This study tests if using epinephrine and tranexamic acid together helps reduce bleeding and improve outcomes during knee replacement surgery. It may be a good fit if you are planning to have knee replacement and do not have certain medical conditions or allergies to these medicines.
Riyadh, Riyadh RegionAges 18–70 - NCT07471555Enrolling by invitation
Vascular access and intraosseous study for nursing students
This trial tests a teaching method for inserting a special needle into bone (intraosseous access) and regular IV lines. It is only for 4th year nursing students.
Valencia, ValenciaAges 18 years+ - NCT07038746RecruitingPhase 1
Inhaled epinephrine for severe allergic reactions during tests or treatment
This trial tests if inhaled epinephrine can safely treat moderate to severe allergic reactions (grade 2 or higher) that can happen during allergy skin tests, oral food or drug challenges, or allergy shots. It is for people who have had such reactions in the past or are at risk and are planning to undergo one of these procedures.
Richmond, British ColumbiaAges 12 years+ - NCT07525687Recruiting
Tourniquet versus epinephrine injection for fibroid removal surgery
This trial compares two methods to reduce bleeding during minimally invasive surgery to remove fibroids (noncancerous growths) from the uterus. You'll receive either a temporary tourniquet (a band that temporarily stops blood flow) or an injection of epinephrine (adrenaline) around the fibroid, and doctors will measure which approach works better and is safer.
MinyaAges 18–45 - NCT06694714RecruitingPhase 4
Testing how long numbing medicine lasts on the nose
This study tests two different numbing medicines on the sides of the nose to see how long each lasts and which works better.
New York, New YorkAges 18 years+ - NCT07409896Recruiting
Comparing two numbing shots for painful lower first molars
This study compares two numbing methods for severe tooth pain (pulpitis) in a lower first molar. If you have a tooth that needs a root canal and the pain lingers after cold, this trial may help determine which anesthetic works better for you.
Rawalpindi, Punjab ProvinceAges 18–55 - NCT06057675RecruitingPhase 2
Tranexamic acid for nose reconstruction after Mohs surgery
This trial tests if tranexamic acid (a medicine that helps blood clot) reduces bleeding and bruising during nose reconstruction after skin cancer removal. It is for adults having a specific type of flap repair on their nose.
Nashville, TennesseeAges 18 years+ - NCT06566352Recruiting
Comparing ways to reduce blood loss during fibroid surgery
This trial tests different methods to minimize blood loss during laparoscopic surgery to remove uterine fibroids. It may help women with heavy bleeding or trouble getting pregnant.
ZagazigAges 18–39 - NCT04964869Recruiting
Epinephrine injection to prevent delayed bleeding after sphincterotomy
This trial tests whether a one-time epinephrine medicine injection can help prevent delayed bleeding after an ERCP procedure called sphincterotomy. You may be considered if you had only brief bleeding right after the procedure and you don’t have certain bleeding-risk conditions.
Taichung, North Dist.Ages 20 years+ - NCT06927999RecruitingPhase 2
Experimental medicine for chronic hives
This trial tests an experimental medicine for chronic hives (called chronic spontaneous urticaria). It is for people whose hives still bother them about once or twice a month despite daily treatment, and who do not have heart problems.
Glenview, IllinoisAges 18–65 - NCT03826524RecruitingPhase 4
Finding the best epinephrine dose after EMS-treated cardiac arrest
This study compares two epinephrine doses during the emergency treatment of out-of-hospital cardiac arrest. It aims to find a dose that works better and more safely for people who are in a shockable heart rhythm when paramedics arrive.
Victoria, British ColumbiaAges 18 years+ - NCT04577690RecruitingPhase 4
PECS pain study for children getting a chest device implanted
This trial tests a pain-control method (PECS) during surgery for children who are having a small chest device implanted. It may help reduce discomfort during and after the operation.
Toronto, OntarioAges 3–18 - NCT05166343RecruitingPhase 2/Phase 3
Testing a shot of epinephrine during out-of-hospital CPR
This trial studies whether giving a medicine shot (epinephrine) into the muscle helps children who have a cardiac arrest outside the hospital. It’s meant for emergency situations where CPR is started right away by trained responders.
London, OntarioAges 1 day–17 years - NCT06456255RecruitingPhase 2/Phase 3
Numbing injection study for first-time sinus surgery
This study tests a numbing medication (bupivacaine with epinephrine) injected during your first sinus surgery to see if it helps reduce pain after the procedure. It may be an option if you have not had sinus surgery before and are generally healthy.
Vancouver, British ColumbiaAges 19 years+ - NCT06471348Recruiting
Pain control after scoliosis surgery: comparing two numbing medicines
This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.
Boston, MassachusettsAges 10–17 - NCT06564987RecruitingPhase 1
Risk of nerve damage from numbing shots for dental work
This study looks at whether a common numbing shot for dental procedures can cause nerve damage. It may help dentists choose safer ways to numb your teeth.
Akron, OhioAges 18–55 - NCT07392580RecruitingPhase 2
Chemo injection before surgery for recurrent throat cancer
This trial tests injecting a chemotherapy drug (cisplatin with epinephrine) directly into throat tumors, given once a week for 3 weeks before planned surgery. It is for people whose throat cancer has come back after radiation and who need surgery to remove it.
Miami, FloridaAges 18 years+ - NCT07638254Recruiting
Buffered vs. Standard Numbing for Dental Pain in Children
This study tests whether a specially prepared numbing medicine works better than standard numbing to reduce pain and anxiety during a dental procedure for children with a painful infected tooth. The goal is to find the gentlest way to numb the area before treatment.
San Luis Potosí City, San Luis PotosíAges 6–12 - NCT07228325Enrolling by invitationPhase 1/Phase 2
Comparing a new epinephrine injector to EpiPen in adults with allergies
This study tests a new epinephrine auto-injector (FMXIN002) compared to the standard EpiPen in people with a history of hay fever or seasonal allergies. The goal is to see if the new device works just as well and is safe in a controlled clinic setting.
MississaugaAges 18–55 - NCT07200778Recruiting
Clamping blood vessels to reduce bleeding during fibroid surgery
This trial tests whether temporarily clamping the main blood vessels to the uterus during laparoscopic fibroid removal can reduce blood loss. It is for women with up to four fibroids who are planning this type of surgery.
MinyaAges 19–45 - NCT07045701Enrolling by invitationPhase 2/Phase 3
Testing FMXIN002 for food allergy reactions
This study is testing a new medicine (FMXIN002) for people who are at risk of a severe allergic reaction to food. If you have a known food allergy and have had a moderate reaction during a food challenge, you may be able to join. The trial will check if the medicine helps prevent or reduce the severity of future reactions.
Be’er Ya‘aqovAges 18–40
What Epinephrine is being studied for
Conditions with recruiting Epinephrine studies.
Common questions
- Are there clinical trials studying Epinephrine?
- Yes. Clin2 currently lists 40 recruiting studies that include Epinephrine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Epinephrine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Epinephrine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Epinephrine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.