Immune tests for tuberculosis diagnosis and management
Part of Infections, Lungs & breathing clinical trials.
This study looks at how the immune system reacts in people with tuberculosis (TB), their close contacts, people with other lung diseases, and healthy volunteers. It aims to find better ways to diagnose and manage TB.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 5 and 65 years old
- You must be able to give consent, or have a guardian who can
- You must fit into one of four groups: active TB, close contact of someone with active TB, other lung disease (like acute infection, sarcoidosis, or lung cancer), or healthy control
- If you have active TB, you must have a confirmed TB infection and be within 14 days of starting treatment
- If you are a close contact, you must have had exposure for at least 6 hours a day for 5 days a week, and have a positive TB skin or blood test, and not be on preventive therapy
- If you have another lung disease, you must have no signs of active TB
- If you are a healthy control, you must have no TB symptoms, no known exposure, and a negative TB skin or blood test
- You cannot have a weakened immune system (like from HIV or immunosuppressive drugs) or be pregnant or suspected to be pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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