Finding the right anesthesia depth for knee replacement
Part of Bones, joints & muscles clinical trials.
This study is testing how deep anesthesia should be during knee replacement surgery to find the best balance. It uses propofol, a common anesthetic, and measures brain activity to guide the dose.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are in good physical health (ASA I or II).
- Your body mass index (BMI) is between 18 and 30.
- You are scheduled for a planned knee replacement on one knee.
- You are willing to follow study procedures and sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing whether adding two medicines (dexamethasone and dexmedetomidine) to the numbing shots (nerve blocks) used during knee replacement surgery can improve pain control and recovery. The study is for people aged 60 to 100 who are having a knee replacement under spinal anesthesia.
This trial tests whether using remimazolam or propofol during hip or knee replacement surgery can lower the risk of postoperative delirium, a sudden, short-term confusion that can happen after anesthesia. It may help people who are at higher risk of postoperative confusion by finding the safer anesthesia approach.
This trial tests two different drugs (dexamethasone and dexmedetomidine) added to a standard nerve block for knee replacement. It aims to see which one provides better pain control after surgery.
This trial tests two different numbing medicines for knee replacement surgery. It compares a long-acting numbing medicine (liposomal bupivacaine) with a standard one (ropivacaine) mixed with other drugs to see which provides better pain control. The goal is to find a way to reduce pain and improve recovery.
This study tests a long-lasting numbing medicine (liposomal bupivacaine) injected around the knee during total knee replacement surgery. It aims to see if this medicine helps control pain and reduce the need for other painkillers after surgery.
This trial compares total intravenous anesthesia (TIVA) with spinal anesthesia for people having a first-time total knee replacement who are expected to go home the same day. The goal is to see which method works better for recovery and comfort.
Hear when a new Knee Osteoarthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.