Clin2
NCT07778498Possibly a fitNot yet recruiting

Study of TJ102 for advanced ovarian cancer

Ovarian Cancer

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study tests a new drug called TJ102 for people with advanced ovarian cancer that has stopped responding to standard treatments. The goal is to see if TJ102 is safe and effective in shrinking tumors.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
150 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have advanced ovarian, fallopian tube, or primary peritoneal cancer that is high-grade serous type.
  • You must have received at least one prior platinum-based chemotherapy and either progressed within 6 months of it (platinum-resistant) or received at least 2 prior platinum lines (if platinum-sensitive).
  • You must have had at least 1 but no more than 4 prior lines of systemic therapy for advanced disease.
  • You must have measurable disease as per standard criteria (RECIST 1.1).
  • You must be 18 years or older and have adequate organ function.
  • You must not have received more than 2 previous antibody-drug conjugate therapies (like mirvetuximab or others).
  • You must not have untreated brain metastases or other cancers within the past 3 years (except minor skin or cervical cancers).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07736937Recruiting· Phase 1/Phase 2
Study of TUB-040 with Standard Drugs for Ovarian Cancer

This study tests a new medicine called TUB-040, given together with standard ovarian cancer drugs like carboplatin and bevacizumab. It is for women with ovarian cancer that has returned after responding to platinum-based chemotherapy and is growing again. The goal is to see if this combination can help control the cancer.

Los Angeles, California
NCT06751485Not yet recruiting· Phase 3
Testing a new drug for platinum-resistant ovarian cancer

This trial tests a new drug called JSKN003 for people with ovarian cancer that has stopped responding to platinum chemotherapy. It aims to see if this drug can shrink tumors or slow cancer growth. If you qualify, you may receive this experimental treatment and be closely monitored by a study team.

NCT06855069Recruiting· Phase 3
A study of HS-20089 for platinum-resistant ovarian cancer

This trial tests a new drug, HS-20089, for people with ovarian cancer that has stopped responding to platinum-based chemotherapy. The goal is to see if the drug can shrink tumors or slow the cancer's growth.

Beijing
NCT04918186Recruiting· Phase 2
Immunotherapy for platinum-resistant ovarian, with tumor testing

This Phase 2 study tests an immunotherapy approach for women whose high-grade serous ovarian cancer came back within 6 months of platinum chemotherapy. It may help shrink tumors and improve control of the disease, but you’ll need tumor biopsies and lab/heart/lung checks to join.

Chicago, Illinois
NCT06930755Recruiting· Phase 1
Study of an oral drug for recurrent ovarian cancer

This study tests a new oral drug called NMS-03305293 for women with recurrent ovarian cancer. It may work by targeting a specific protein involved in cancer growth. You may be eligible if you have high-grade serous ovarian cancer, have had limited prior treatments, and do not have a BRCA mutation.

Peoria, Illinois
NCT07214779Recruiting· Phase 3
New drug vs chemo for platinum-resistant ovarian cancer

This study tests a new drug (INCB123667) given as a pill, compared to standard chemotherapy, for people whose ovarian cancer has stopped responding to platinum-based treatments and whose tumor has high levels of a protein called Cyclin E1. The goal is to see if the new drug works better than standard chemo for this specific type of cancer.

Anchorage, Alaska

Hear when a new Ovarian cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.