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NCT07738341Possibly a fitNot yet recruiting

GB268 alone or with other drugs for advanced breast cancer

Breast Cancer (Locally Advanced or Metastatic)

Treatments studied

Part of Cancer, Skin clinical trials.

This study tests a new drug called GB268, either alone or with other medicines, for people with advanced breast cancer. It may help by targeting cancer cells in a new way, and the study will check if it shrinks tumors or slows the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
270 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You have a type of breast cancer called triple-negative (TNBC) or HR+/HER2- that has spread or cannot be removed with surgery.
  • You have not had certain prior treatments — the exact rules depend on which group (cohort) you join.
  • You have at least one tumor that can be measured on a scan.
  • You have not received an immune checkpoint inhibitor before (except in early-stage treatment, if relapse was more than 12 months ago).
  • You need to provide a tissue sample (from a previous biopsy) for testing.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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