Immune cells for advanced soft tissue sarcoma
Treatments studied
Part of Cancer clinical trials.
This trial tests a treatment made from your own immune cells, called tumor-infiltrating lymphocytes, to see if they can shrink or slow down advanced soft tissue sarcoma. It might be an option if you have tried other treatments and your cancer is still growing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 16 years or older.
- You have a type of soft tissue sarcoma called undifferentiated pleomorphic sarcoma (UPS) or dedifferentiated liposarcoma (DDLPS) that cannot be removed with surgery or has spread.
- You have had at least 1 and up to 3 prior treatments, including a type of chemotherapy called anthracycline.
- Your cancer has grown after your last treatment.
- You have at least one tumor that can be removed for the treatment, and another tumor that can be measured after surgery.
- You are generally well enough to have surgery and receive intensive care.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a precision medicine approach by giving targeted therapy before surgery for high-risk soft tissue sarcoma. The goal is to see if matching treatment to your tumor's type can improve outcomes.
This trial combines cryoablation (a freezing technique to destroy tumors) with camrelizumab (an immunotherapy drug that helps your immune system fight cancer) for patients with advanced soft tissue sarcoma that hasn't responded to standard treatments. The goal is to see if this combination works better than current options.
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