Clin2
NCT07743255Possibly a fitEnrolling by invitation

Preventing migraines in children with melatonin and propranolol

Migraine Disorders

Treatments studied

Part of Brain & nervous system clinical trials.

This study tests whether two common medicines, melatonin and propranolol, can help prevent migraines in children. If your child has frequent, disabling migraines, this treatment might reduce how often they occur and improve daily life.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
60 people
Ages
5 years to 15 years
Study type
Interventional

Who can take part

  • Your child must be between 5 and 15 years old.
  • Your child must have a confirmed diagnosis of migraine, with or without aura, by a doctor.
  • Migraines must be causing moderate to severe disability, with a score of 11 or higher on the PEDMIDAS scale.
  • Your child cannot have other serious brain or nerve conditions, like epilepsy or brain tumors.
  • Your child cannot be currently taking preventive migraine medication, or have taken it in the last 4 weeks.
  • Your child cannot have a diagnosed primary sleep disorder unrelated to migraines, or an allergy to melatonin or propranolol.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05889624Recruiting
Study of treatments for childhood migraine headaches

This study looks at ways to help children and teens with migraine headaches by testing a care approach that includes access to evidence-based treatment. It may help if your child has frequent migraine headaches and is starting (or not already on) certain migraine-preventive medicines.

Birmingham, Alabama
NCT07354126Recruiting
Flunarizine vs. propranolol for migraine in children

This trial tests two medicines—flunarizine and propranolol—to see which one works better for preventing migraines in children ages 8 to 15. If your child has frequent migraines that affect their daily life, this study may help find a treatment that works for them.

Lahore, Punjab Province
NCT07655700Not yet recruiting· Phase 4
Comparing two migraine prevention medicines and their combination

This study tests three ways to prevent migraines: propranolol, flunarizine, or both together. If you have frequent migraines, this might help find which treatment works best for you.

Chittagong
NCT07147972Not yet recruiting· Phase 3
Comparing two preventives for episodic migraine headaches

This trial compares two medicines taken daily to prevent migraine headaches, with the goal of reducing how often they happen.

NCT04649242Recruiting· Phase 3
Migraine pain relief study for kids and teens

This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.

Birmingham, Alabama
NCT06972056Recruiting· Phase 4
Comparing migraine prevention drugs: atogepant, propranolol, topiramate

This study compares three common migraine prevention medications to see which works best. You might be able to join if you have migraines at least 4 days a month and haven't taken these specific drugs before.

Flagstaff, Arizona

Hear when a new Migraine Disorders trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.