Study of an experimental pill for uncontrolled moderate to severe asthma
Part of Immune system & allergy, Lungs & breathing clinical trials.
This study tests an investigational drug (called JNJ-95597528) taken as a pill, to see if it can reduce asthma attacks and improve control in people with moderate to severe asthma that isn't well controlled by current inhalers. It may be a new option to help reduce airway inflammation and improve your breathing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a doctor's confirmed diagnosis of asthma that is not well controlled despite daily treatment.
- For at least 3 months, you've been on a medium or high daily dose of an inhaled corticosteroid (anti-inflammatory inhaler) and at least one other controller medicine (like a long-acting bronchodilator).
- You've shown signs that your airways are changeable (like a positive response to a bronchodilator or a positive challenge test) in the past 3 years.
- You are not a current smoker, and if you previously smoked, you quit at least 6 months ago and have less than a 20 pack-year history.
- You haven't needed oral steroids or been hospitalized for asthma in the 2 weeks before screening.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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