Orlistat for metabolic and hormonal health in PCOS
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study tests whether the weight-loss drug orlistat can improve blood sugar, hormones, and other metabolic measures in women with polycystic ovary syndrome (PCOS). If you have PCOS and are overweight, this treatment might help with symptoms like irregular periods and excess hair growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 to 45.
- You have been diagnosed with PCOS based on the Rotterdam criteria, meaning you have at least two of: irregular or absent periods, signs of high male hormones (like acne or excess hair), or polycystic ovaries on ultrasound.
- Your body mass index (BMI) is between 18.5 and 35, using Asian cutoffs.
- You are not currently taking or recently stopped taking certain medications or supplements that affect hormones or metabolism, such as birth control pills, fertility drugs, weight-loss pills, or cholesterol medicines, or natural supplements like inositol or cinnamon.
- You are not undergoing IVF treatment, and you are not pregnant, breastfeeding, or menopausal.
- You do not have certain other health conditions, such as thyroid problems, diabetes, or severe liver or kidney disease.
- Your AMH level is at least 0.7 ng/mL (a hormone related to ovarian reserve).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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