A study of a specific enzyme in osteoarthritis and ankylosing spondylitis
Part of Bones, joints & muscles clinical trials.
This study looks at a specific enzyme (15-hydroxyprostaglandin dehydrogenase) in people with osteoarthritis or ankylosing spondylitis. It may help researchers understand these conditions better and find new treatment targets.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with osteoarthritis (OA) or ankylosing spondylitis (AS)
- You do NOT have other types of inflammatory arthritis like psoriatic arthritis, gout, or lupus arthritis
- You do NOT have a joint infection or suspected joint infection
- You have not had a steroid injection into a joint in the past 3 months
- You are not taking NSAIDs (non-steroidal anti-inflammatory drugs) that could affect the results
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is looking for people with ankylosing spondylitis, rheumatoid arthritis, or lupus to help find biomarkers that may make diagnosis easier. If you have one of these conditions and haven't tried biologic therapies, you may be able to join.
This trial is for people with ankylosing spondylitis (a type of arthritis that affects the spine) who are otherwise healthy. It may test a treatment to see if it helps control symptoms, whether your disease is active or stable.
This trial measures levels of a protein called CCL-21 in the blood of people with rheumatoid arthritis, osteoarthritis, and healthy volunteers. The goal is to see if CCL-21 levels relate to disease activity and could help track inflammation.
This study examines joint tissue from people with different types of arthritis to understand the disease better. It may help researchers develop better treatments in the future.
This study tests the safety of an experimental injection called OA-SYS for people with moderate to severe knee osteoarthritis. It may help if you have not had recent injections or certain other health problems.
This study looks at bone and muscle health in people with axial spondyloarthritis. It compares their bone density and muscle strength to healthy volunteers to see if there is a link with a condition called osteosarcopenia.
Hear when a new Osteoarthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.