Enzyme levels in osteoarthritis and ankylosing spondylitis
Part of Bones, joints & muscles clinical trials.
This study looks at the levels of a specific enzyme (15-hydroxyprostaglandin dehydrogenase) in the blood and joints of people with osteoarthritis or ankylosing spondylitis. The goal is to see if this enzyme can help tell these conditions apart or show how active they are.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years old or older.
- You must have been diagnosed with ankylosing spondylitis (by a doctor using standard criteria) OR osteoarthritis of the hip, knee, or hand (by a doctor using standard criteria).
- You cannot have other types of inflammatory arthritis, such as psoriatic arthritis, gout, or lupus-related arthritis.
- You cannot have a joint infection or suspected infection in the joint.
- You cannot have had a steroid injection into the joint recently (within a time that might affect the test).
- You cannot be taking non-steroidal anti-inflammatory drugs (NSAIDs, like ibuprofen or naproxen).
- You must not have a major illness that could affect the test results or ultrasound readings.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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