CAR T-cell therapy for children and young adults with certain sarcomas
Part of Cancer clinical trials.
This trial tests a new kind of cell therapy called CAR T-cells that are engineered to find and attack sarcoma cells carrying a marker called B7-H3. It is for children and young adults whose sarcoma has come back or not gone away after treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 1 and 24 years old.
- Have a type of sarcoma called rhabdomyosarcoma, Ewing sarcoma, or desmoplastic small round cell tumor.
- The tumor must have a specific protein called B7-H3 that the therapy targets.
- The cancer must have come back or not responded to at least one prior treatment.
- A scan must show visible tumors that can be measured in the body.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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