Comparing rimegepant and flunarizine for preventing vestibular migraine
Treatments studied
This trial tests a new medication called rimegepant (a CGRP inhibitor, which targets a protein involved in migraine) against flunarizine (a commonly used preventive) for vestibular migraine. It aims to see if rimegepant works as well as flunarizine in reducing vertigo and dizziness episodes. If you qualify, you may receive one of these medications for several months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You must have a diagnosis of definite vestibular migraine (or meet the criteria for it), with at least 5 episodes of vertigo or dizziness lasting 5 minutes to 72 hours.
- You must have had at least 4 days with moderate or severe dizziness or vertigo during the 4 weeks before the study starts.
- You must be willing to use a smartphone or computer to fill out a daily electronic diary and have access to email.
- You cannot have taken certain migraine prevention drugs (like flunarizine or CGRP inhibitors) before.
- You cannot have certain other ear or balance disorders (like Meniere's disease, vestibular neuritis, or inner ear balance loss).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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