Clin2
NCT07754682Possibly a fitNot yet recruiting

Antibody infusions vs. antibiotics after CAR-T therapy

Chimeric Antigen Receptor T-cell TherapyB Cell Acute Lymphoblastic Leukemia (B-ALL)B Cell LymphomaAntibiotic ProphylaxisImmunoglobulin Therapy

Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.

This study compares two ways to help prevent infections after CAR-T cell therapy: regular antibody infusions (immunoglobulins) versus taking antibiotics. If you have low antibody levels after CAR-T treatment, this trial may help decide which approach works better for you.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
228 people
Ages
16 years to 80 years
Study type
Interventional

Who can take part

  • You are between 16 and 80 years old.
  • You have a type of blood cancer called B-cell acute lymphoblastic leukemia or B-cell lymphoma.
  • Your antibody levels (gamma globulins) are low, below 4 g/L, as shown by a blood test.
  • You have received or will receive CAR-T cell therapy (a treatment that uses your own immune cells).
  • If you could become pregnant, you must agree to use reliable birth control during the study and for 12 months after CAR-T infusion.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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