HX15001 with etrasimod for moderate-to-severe ulcerative colitis
Part of Digestive system clinical trials.
This study tests a new combination treatment for moderate-to-severe ulcerative colitis (UC). The goal is to see if adding an investigational drug to an existing UC therapy helps reduce symptoms and improve the lining of the colon.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older (or meet local age requirements) and weigh at least 40 kg.
- You have had ulcerative colitis for at least 3 years, and your disease is moderate to severe.
- You have tried biologic drugs (like anti-TNF, vedolizumab) or JAK inhibitors and they did not work well enough.
- You have not had your colon removed, and you don't have a colostomy or ileostomy.
- You are willing to use birth control if you or your partner could become pregnant.
- You are willing to have regular check-ups, blood tests, and colonoscopies as part of the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study watches how well etrasimod works for adults with moderate to severe ulcerative colitis (UC). You must already be prescribed etrasimod by your doctor, and the study collects information through a web-based tool.
This study tests an investigational drug for people with active mild-to-moderate ulcerative colitis. It aims to see if the drug can improve symptoms without needing advanced treatments like biologics.
This trial tests new medicines for people with moderate to severe ulcerative colitis who haven't found relief with standard treatments. Participants will receive one of several investigational drugs (these are not yet approved and are being studied for safety and tolerability). The goal is to see if the drugs are safe and if they might help control symptoms.
This trial tests if the medicine etrasimod can help children with moderate to severe ulcerative colitis. You may still be able to join even if you are already taking other treatments for your condition.
This study tests an investigational pill for people with moderate-to-severe ulcerative colitis that has not improved with standard treatments. The goal is to see if the pill can reduce symptoms like bloody stools and frequent bowel movements.
This trial tests a new medicine (TQH3906) for people with moderate to severe ulcerative colitis or Crohn's disease that hasn't improved with other treatments. The goal is to see if it can help control inflammation in the gut.
Hear when a new Colitis, Ulcerative trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.