Clin2
NCT07769255Possibly a fitRecruiting

Nebulized dexmedetomidine for early chronic migraine

Chronic Migraine

Treatments studied

Part of Brain & nervous system clinical trials.

This trial tests whether a medicine called dexmedetomidine, given through a nebulizer (mist you breathe in), can help reduce the number of headache days and prevent migraines from becoming chronic. It is for people who have recently started having many headache days each month.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
146 people
Ages
18 years to 55 years
Study type
Interventional

Who can take part

  • You have had migraine with 15 or more headache days per month for less than 6 months.
  • You have not taken any migraine prevention medication in the last 8 weeks.
  • You do not have heart, lung, psychiatric, or other neurological conditions.
  • You are not currently taking sedatives, opioids, or CGRP-targeting therapies.
  • You are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06428838Enrolling by invitation· Phase 3
Add-on migraine treatment for emergency room visits

This study tests an add-on migraine medicine (eptinezumab) given in the emergency room to quickly relieve a migraine attack, in addition to the usual care. It aims to see if this approach reduces pain and prevents the migraine from coming back.

New Westminster, British Columbia
NCT06641206Recruiting
Dexmedetomidine injection for chronic knee pain

This trial tests whether a single injection of dexmedetomidine into the knee joint can reduce chronic knee pain. It is for people who are not scheduled for knee surgery and have no serious health problems.

Tanta, El Gharbyia
NCT06935552Not yet recruiting· Early Phase 1
Ketamine and lidocaine infusions for hard-to-treat chronic migraine

This study tests whether giving two pain-relieving medicines, ketamine and lidocaine, through an IV can help adults with chronic migraine that hasn't improved with other treatments. The goal is to see if this treatment reduces migraine pain and improves daily life.

NCT07480304Enrolling by invitation
Dexmedetomidine mist for stable breathing tube placement

This trial tests if a medication called dexmedetomidine (given as a mist through a nebulizer) can help keep your heart rate and blood pressure steady when a breathing tube is placed for surgery. It may be an option for people having planned surgery who want a smoother experience.

Karachi, Sindh
NCT05306899Recruiting· Phase 3
IV ketamine for chronic daily headaches

This trial tests whether an IV dose of ketamine can reduce chronic daily headaches and is safe for people with this condition. It may help by lowering headache frequency and severity, but it also has several medicine and health-related safety checks.

Toronto, Ontario
NCT06251375Not yet recruiting· Phase 4
Early sedation for older patients on breathing machines

This study tests an early sedation medicine called dexmedetomidine in patients 65 and older who need a breathing tube. It may help reduce confusion and time on the machine compared to usual care.

Toronto, Ontario

Hear when a new Chronic Migraine trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.