Rituximab and steroids for pemphigus
Treatments studied
Part of Immune system & allergy, Skin clinical trials.
This trial compares two treatment combinations for moderate-to-severe pemphigus: rituximab plus steroids versus steroids plus azathioprine. The goal is to find which approach controls the disease better while reducing side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must have moderate to severe pemphigus vulgaris that is either newly diagnosed or flaring up.
- Your diagnosis must be confirmed by a skin biopsy and a special test called direct immunofluorescence.
- You cannot be pregnant or nursing, and you must not have a serious infection or active cancer.
- You must not have had rituximab treatment within the last 12 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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