Testing rituximab plus AB-101 for autoimmune diseases
Treatments studied
Part of Bones, joints & muscles, Heart & circulation, Immune system & allergy, Lungs & breathing, Skin clinical trials.
This trial tests a new treatment (AB-101) combined with rituximab for people with certain autoimmune diseases like rheumatoid arthritis, pemphigus vulgaris, vasculitis, or lupus. It is for those who have not had success with standard therapies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have one of these conditions: rheumatoid arthritis, pemphigus vulgaris, vasculitis (GPA/MPA), or lupus.
- You have tried at least two standard treatments for your condition and they didn't work or caused side effects.
- You are taking a stable, low dose of steroids (less than 20 mg prednisone a day) for at least a month.
- You have not had rituximab or other similar treatments in the last 3 months, and no prior cell therapy.
- Your heart, lungs, kidneys, and blood counts meet specific healthy levels.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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