Clin2
NCT07770282Possibly a fitNot yet recruiting

Semaglutide for heart health in schizophrenia with metabolic syndrome

Schizophrenia DisorderMetabolic SyndromeAntipsychotic-induced Weight GainCardiovascular RiskInsulin Resistance

Part of Hormones & metabolism, Mental health clinical trials.

This study tests whether semaglutide (a medicine used for diabetes and weight loss) can improve heart health and blood sugar in people with schizophrenia who also have metabolic syndrome. It may help lower the risk of heart problems in this group.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
600 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You have schizophrenia and have been taking one of the newer antipsychotic medicines for at least 6 months.
  • You also have metabolic syndrome (a group of conditions that increase heart risk, like high blood sugar, high blood pressure, and extra belly fat).
  • You are older than 25 years.
  • You are not taking clozapine, aripiprazole, or a combination of antipsychotics.
  • You do not have any serious medical or brain conditions, and you are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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